20 Propylthiouracil Mechanism, Uses, and Risks
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YouTubePharmacology
20 Propylthiouracil Mechanism, Uses, and Risks
Propylthiouracil (PTU) is an antithyroid medication belonging to the thioureylene class. Its primary use is in the management of hyperthyroidism, a condition characterized by the overproduction of thyroid hormones (thyroxine - T4 and triiodothyronine - T3) by the thyroid gland. While it has been largely superseded by another drug, Methimazole ...
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Propylthiouracil, methimazole, levothyroxine - Free Sketchy Medical Lesson
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sketchy.comSep 4, 2022
🟣 PROPYLTHIOURACIL: Blocks TPO & 5’-deiodinase. Used in pregnancy (1st trimester). ⚠️ Hepatotoxic. πŸ”΅ METHIMAZOLE: TPO inhibitor for 2nd/3rd trimester. ⚠️ Teratogenic early on. ☒️ RADIOACTIVE IODINE: Destroys thyroid. Not for kids or pregnant patients! 🟠 PROPRANOLOL: Beta-blocker that blocks peripheral T4 to T3 conversion. ⚠️ Watch for bradycardia. πŸ’Š LEVOTHYROXINE = T4. πŸ’Š LIOTHYRONINE = T3. πŸ›‘ FACTITIOUS THYROTOXICOSIS: Exogenous hormone use β†’ suppressed TSH! πŸ‘‰ FOLLOW for more fast-track ph
🟣 PROPYLTHIOURACIL: Blocks TPO & 5’-deiodinase. Used in pregnancy (1st trimester). ⚠️ Hepatotoxic. πŸ”΅ METHIMAZOLE: TPO inhibitor for 2nd/3rd trimester. ⚠️ Teratogenic early on. ☒️ RADIOACTIVE IODINE: Destroys thyroid. Not for kids or pregnant patients! 🟠 PROPRANOLOL: Beta-blocker that blocks peripheral T4 to T3 conversion. ⚠️ Watch for bradycardia. πŸ’Š LEVOTHYROXINE = T4. πŸ’Š LIOTHYRONINE = T3. πŸ›‘ FACTITIOUS THYROTOXICOSIS: Exogenous hormone use β†’ suppressed TSH! πŸ‘‰ FOLLOW for more fast-track ph
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