MOUSE POOP VS RAT POOP: HOW TO IDENTIFY AND CLEAN UP DROPPINGS HOW TO CLEAN UP RAT & MOUSE POOP SAFELY Open the doors and windows – Ventilate the room for at least 30 minutes before you begin cleaning. Wear protective gear – Use rubber gloves, so you don’t touch the waste directly; a face mask, so you don’t inhale the dust (as we said, diseases can be transmitted by inhaling polluted dust); even consider wearing protective goggles, so contaminated dust doesn’t get into your eyes. Spray with a 10