is an open access journal by BMJ and BCS, publishing original research in cardiovascular medicine. Open Heart considers submissions of a variety of article types, including original research articles, ...
Background Hereditary transthyretin amyloidosis (ATTRv) is a rare multisystem disorder with marked phenotypic heterogeneity.
The natural history of symptomatic severe aortic stenosis (AS) heralds a poor prognosis—a paradigm that rightly drives valve ...
Background Atrial fibrillation (AF) is a common cause of ischaemic stroke and a major global health burden, but is often ...
Background Out-of-hospital cardiac arrest (OHCA) in children is a rare but devastating event, with an estimated incidence of ...
Background Heart failure (HF) remains associated with high mortality worldwide despite advances in guideline-directed therapy ...
Cardiovascular disease (CVD) is the most common cause of death in women. Early identification of CVD risk factors in women is often overlooked by physicians leading to delays in diagnosis and ...
Background This study aimed to explore the association of long-term left ventricular assist device (LVAD) support with changes in inflammation and cardiac remodelling in subjects with advanced heart ...
Objective To investigate whether aligning exercise timing with chronotype enhances cardiometabolic and sleep-related benefits in sedentary adults with cardiovascular risk factors. Methods In this ...
Background Japanese guidelines recommend a corticosteroid maintenance dose of 5–10 mg/day for cardiac sarcoidosis (CS); however, the optimal dose remains unclear. This study aimed to evaluate the ...
Background Patients with severe aortic stenosis (AS) are at high risk of mortality, regardless of symptom status. Despite this, aortic valve replacement rates remain low for patients with severe AS ...
Background The role of mineralocorticoid receptor antagonists (MRAs) in acute myocardial infarction (MI) remains controversial, with conflicting evidence from landmark trials. We aimed to assess the ...
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