The San Francisco 49ers are making an interesting change to their coaching staff. Head coach Kyle Shanahan on Wednesday in ...

Running back is one position that won't land particularly high on a list of San Francisco 49ers needs in the 2025 NFL draft.

According to Wagoner, San Francisco is interested ... of The Athletic reports. The 49ers' 2024 campaign is over, but the team's season finale included yet another RB injury. On only his second ...

San Francisco 49ers rookie RB Isaac Guerendo suffered MCL and ankle sprains against the Arizona Cardinals, avoiding an ACL ...

The San Francisco 49ers have had to deal with multiple running back injuries this season and another went down in Week 18 ...

San Francisco 49ers running back Isaac Guerendo is set to return from foot and hamstring injuries and play Monday vs. the ...

GLENDALE -- San Francisco 49ers RB Isaac Guerendo was carted off the field in Week 18's matchup against the Arizona Cardinals. He has already been ruled out with a knee and ankle injury. On just the ...

While the Lions are preparing to make a deep run in the playoffs, the 49ers have lost their last two games and have dropped ...

After missing San Francisco's Week 16 loss to the Miami Dolphins, 49ers rookie running back Isaac Guerendo reportedly is ...

The San Francisco 49ers' miserable 2024 season is mercifully over. Attention for the Niners will quickly turn to their ...