Buffalo Bills outside linebacker Greg Rousseau scoops up a fumble recovery as San Francisco 49ers quarterback Brock Purdy ...

Josh Allen scored a receiving touchdown on a pass he threw in his latest do-everything performance, and the Buffalo Bills ...

San Francisco 49ers star running back Christian McCaffrey departed Sunday night's snow game against the Buffalo Bills early ...

The 49ers look to turn around their season with a win in Buffalo against the Bills, who are chasing the top seed in the AFC.

The 49ers were absolutely shellacked Sunday for a second straight week as the Buffalo Bills beat them 35-10 on national ...

Brandon Allen is 2-8 in 10 career starts. One of them was against Josh Allen and the Bills but Brandon Allen wore No. 2 in ...

Check out who's in and who's out for Week 13. Plus weather reports, last-minute free agency options, and Jake Ciely's fantasy ...

San Francisco 49ers could use some good news on the injury front, especially as they face the (9-2) Buffalo Bills for Week 13 ...

San Francisco 49ers quarterback Brock Purdy is poised to return to action on Sunday night against the Buffalo Bills after ...

The San Francisco 49ers released their list of seven inactive players for Sunday night's game against the Buffalo Bills, ...

A pair of Super Bowl hopefuls from each conference meet up on Sunday, Dec. 1 to close out the NFL schedule for the day with ...

The 49ers take on the Bills on "Sunday Night Football" in Week 13. Here's the latest on if QB Brock Purdy will be available for San Francisco.