The odds of achieving a perfect bracket for the college basketball tournament are about 1 in 9.22 quintillion.
The final game of the First Four pits two No. 16 seeds against each other as High Point takes on William & Mary.
McNeese State nearly squandered its 24-point second-half lead, but Clemson's comeback was too late, and the Cowboys pulled off the upset.
The NCAA will also stream games via its March Madness Live option. The top betting favorites as the tournament arrives are (in order) Florida, Duke, Auburn and Houston, according to BetMGM Sportsbook.
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