The Buffalo Bills have the chance to make team history on "Sunday Night Football" against the San Francisco 49ers.

San Francisco 49ers defensive end Nick Bosa (97) celebrates after sacking Tampa Bay Buccaneers quarterback Baker Mayfield ...

Buffalo Bills quarterback Josh Allen and coach Sean McDermott reacted to forecasts of a snow game against the San Francisco ...

San Francisco 49ers defensive end Nick Bosa missed Wednesday's practice as the team began preparations for Sunday's game ...

You can listen on SiriusXM satellite radio on channel 225 (Bills feed) and channel 226 (49ers feed), and on traditional radio ...

The four-time defending AFC Champs squared off against the Detroit Lions in one of a number of Thanksgiving matchups between ...

After its Week 11 party in Buffalo, "The NFL Today" crew is hitting the road again. This time, the NFL on CBS pregame show ...

With the Bills (9-2) on the cusp of a fifth straight AFC East division title, the pressure is on Allen and Co. to deliver the ...

Christen Harper Goff, Alix Earle, Sarah Jane Ramos and more NFL WAGs share with PEOPLE exclusively how they creatively plan ...

The Buffalo Bills will play the San Francisco 49ers at home at Highmark Stadium on “Sunday Night Football” in Week 13. The ...

Now that the holiday season is in full swing, several Bills players are taking the time to be active in the community. A ...

Josh Allen put the Buffalo Bills on his back with his legs. Buffalo's quarterback delivered the knockout punch to hand the ...