Sickle cell trait (SCT) is a genetic condition where individuals carry one copy of the sickle cell gene, making them carriers but generally symptom-free. This trait can be passed to offspring, ...

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A single base change can create a devastating genetic disorder or a beneficial adaptation, or it might have no effect. How do mutations happen, and how do they influence the future of a species?

Dr Layan Allawi – NHS England Sickle Cell and Thalassaemia Clinical Fellow – describes her experience of carrying the sickle cell trait and its relation to sickle cell disease. When I was young, I was ...

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Abstract: Sickle cell anemia is a genetic disease characterized by a genuine alteration of hemoglobin that leads to the emergence of sickle-shaped red blood cells. The clinical diagnosis of sickle ...