The world’s first personalised mRNA cancer jab for melanoma has cut the risk of patients dying or cancer returning by 42% when combined with immunotherapy, a large trial shows. The drug, which was ...

Meghan Markle says she is “deeply distressed” by allegations that father Thomas Markle Sr possessed child abuse images. He denies the claims.

TV and radio presenter Rylan Clark was coached by ex-Gogglebox star and ‘Master of Mischief’ George Baggs to master the perfect real-life jump scare.

Here is everything you need to know about clock changes in the UK this year. In autumn the clocks will go back at 2.00am on the final Sunday of October, which this year falls on Sunday, October 25. It ...

In a statement first reported by the Sun and issued to the Press Association, Meghan said: “I am deeply distressed at the news that has come to light in the last 24 hours, and m ...

This autumn MatchWornShirt is proud to stand together with football clubs throughout the UK in support of the Royal British Legion’s Poppy Appeal.

Just before 11am on Friday, more than 16,000 homes were without power in the South West thanks to Storm Austen.

Total new work across the private sector increased at its fastest rate since September 2024 as firms highlighted a “general recovery” in customer demand. A number of surveyed ...

Scotland is braced for heavy rain on Friday as the first of two named storms sweeps in. A Met Office yellow warning for rain came into force at 7am and lasts until midnight as Storm Austen hits the ...

Boss Andy Spencer said the company has started the new financial year with ‘real confidence’ despite economic pressures on the pub sector.

This year's I'm a Celebrity lineup is tipped to be "one of the wildest yet", with Jeremy Clarkson and Wayne Rooney among the big names rumoured to be entering the jungle.

New weather warnings have been announced for parts of Ireland, as the island deals with two named storms in quick succession. Impacts are expected to include flooding, difficult travelling conditions ...