How much do blood-based biomarkers help in diagnosing Alzheimer’s disease? Quite a lot, according to scientists led by Albert Puig Pijoan and Marc Suárez-Calvet at the Hospital del Mar in Barcelona, ...

In the latest development on diagnostic methods for Alzheimer’s disease going mainstream, the U.S. Food and Drug Administration approved clinical use of Lantheus’ tau PET tracer florquinitau, aka ...

Scientists offer new clues as to how overzealous neuronal firing may fuel synaptic loss in early Alzheimer's. In Science July 9, scientists led by Soyon Hong at University College London report that ...

Researchers propose unifying TDP-43 proteinopathies under one umbrella. TDP-43-associated neurodegenerative disease (TAND) would include ALS, FTD, and LATE. A machine learning algorithm, MARBLE, ...

A blood test may be almost as good as a brain scan for determining where someone lies along the Alzheimer’s disease continuum. So conclude scientists led by Gemma Salvadó and Oskar Hansson at Lund ...

CAR-T cell therapy has practically become a household name, given its success in taking down blood cancers. The chimeric antigen receptors used in this type of cell therapy are designed to sic killer ...

White-matter hyperintensities, a sign of damage to the brain’s vasculature, are common on MRI scans of people with Alzheimer’s disease. Do they indicate an independent vascular co-pathology, or are ...

In the setting of Alzheimer’s and other neurodegenerative diseases, do T cells make things better, or worse? A simple answer just won’t do—it likely depends on the type of T cells, where they are in ...

Clinicians have started using blood tests of p-tau217, a marker of amyloid plaques, to help diagnose AD in routine patient care, not just research studies. Alas, at AD/PD 2026, held March 17-21 in ...

The notion that lithium might treat Alzheimer’s was revived last year when scientists reported that the brains of people and mice with amyloid pathology are deficient in the metal ion, and that the ...

A community cohort boasting 16,000 participants? A memory clinic that sees more than 2,000 patients per month? A countrywide goal of screening 80 percent of its aged population for AD? These are a few ...

According to a recent study, the view that Alzheimer’s disease damages the brain irreversibly might need to change. In December 22 Cell Reports Medicine online, scientists led by Andrew Pieper of Case ...