The Buffalo Bills will look to lock up a playoff spot in their Week 13 showdown with the San Francisco 49ers. Here are five ...

T he Buffalo Bills are coming off their bye week and getting set for the final six-game stretch of the season, beginning at ...

The Buffalo Bills (9-2) bring a six-game winning streak into a matchup with the San Francisco 49ers (5-6) on Sunday, December ...

Watch out for the tables on "Sunday Night Football." The nightcap of Sunday's action will be in northern New York with the ...

Buffalo Bills head coach Sean McDermott has ruled out tight end Dalton Kincaid for Sunday night's game against the San ...

The San Francisco 49ers are up against the Buffalo Bills in Week 13. The 49ers have dealt with an array of injuries this ...

Providing the betting odds and our preview and prediction for the star-studded matchup between the San Francisco 49ers and ...

One thing does not change, though. The defending NFC champion 49ers are 5-6 and they need to get on a heater - which will be ...

The Bills’ defense has plenty of experience against 21 personnel because Miami runs it the second most of any team in the NFL ...

The Buffalo Bills have the chance to make team history on "Sunday Night Football" against the San Francisco 49ers.

Check out the top 10 catches from San Francisco 49ers tight end George Kittle from his eight year career, so far.

Under head coach Kyle Shanahan, the San Francisco 49ers have spent years falling just inches short of the franchise’s sixth ...