The central dogma of biology defines the flow of genetic information: It describes how proteins are made from mRNA templates, which are in turn made from DNA. Exporting the mRNA from inside the ...

Anya Hillery, Ph.D., SLU-Madrid health sciences professor currently on excedencia, publishes "mRNA Therapeutics: Foundations, Innovations and Clinical Applications" with the help of SLU's prestigious ...

In the fast-evolving field of medical science, a new artificial intelligence model may be about to change the way mRNA-based ...

The goal of my laboratory is to define the sequence-structure-function relationships that underpin mRNA regulation and non-coding function in cells. We aim to translate our findings into mechanistic ...

Researchers from the Broad Institute and Massachusetts Institute of Technology (MIT) have engineered multi-tailed mRNAs that boost mRNA activity levels in cells by as much as 20x and last 2-3 times ...

Although the concept of using synthetic oligonucleotides to modulate RNA function was described as early as 1978, 1 its realization in the form of drugs approved by the Food and Drug Administration ...

Researchers at Arizona State University’s (ASU) School of Molecular Sciences and the Biodesign Institute’s Center for the Mechanism of Evolution have discovered an unprecedented pathway producing ...

We report that mice lacking the heterogeneous nuclear ribonucleoprotein U (hnRNP U) in the heart develop lethal dilated cardiomyopathy and display numerous defects in cardiac pre-mRNA splicing. Mutant ...