Manchester United hope to win their first Premier League match in a month when they host last-place Southampton.

Southampton under Ivan Juric are very different to the way they played under previous boss Russell Martin because most of the time they just lump it forward now, and they are far more direct.

Manchester United will be without one key player for tonight’s Premier League clash against Southampton. Diogo Dalot’s two yellow cards against Arsenal in the FA Cup penalty shootout win means he serves a one-game suspension for the midweek clash at Old Trafford.

Manchester United and Southampton FC square off Thursday in their second matchup in the Premier League this season after Manchester United took the first game 3-0. It starts at 3:00 PM ET on

Man United have been promising with their performances over a few weeks and will hope to avoid any upset when they host the Saints at Old Trafford this time.

Prediction for the Premier League match between Manchester United vs Southampton, which will take place on January 16th. Who will turn out to be stronger? Check the teams' conditions! Several betting options are available.

The best betting opportunity comes from the player card markets at Old Trafford as this clash combines the best top-flight referee for cards with the side possessing the poorest discipline.