eLife

Conformational Variability of HIV-1 Env Trimer and Viral Vulnerability

In silico antibody accessibility analysis indicates that ectodomain epitopes are transiently exposed, while MPER epitopes are virtually always occluded in the pre-fusion trimer.
Nature

HIV-1 A-rich RNA loop mimics the tRNA anticodon structure

Figure 1: a, Sequence and secondary structure of the A-rich loop of HIV-1 RNA. These possible mechanisms should be investigated further by biochemical and genetic experiments. The RNA molecules of HIV ...
Fierce Biotech

Gilead study finds HIV can evolve to resist lenacapavir, but doing so hampers the virus' replication

Now, Gilead has conducted an analysis of a phenomenon that can undermine all infectious disease therapies, including ...
C&EN

Structure-Based Identification of HIV-1 Nucleocapsid Protein Inhibitors Active against Wild-Type and Drug-Resistant HIV-1 Strains

Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology, Temple University, BioLife Science Bldg., Suite 333, 1900 N 12th Street, ...
verywellhealth

A Look at Global HIV Statistics

40.8 million people around the world are living with HIV. In 2024, 1.3 million people were newly infected with HIV. 13% of people with HIV didn't know they had it in 2024. Global HIV statistics can ...