A compact Cas12f nuclease shows high editing efficiency in human cells, with structural insights enabling an engineered variant potentially suited for future AAV‑compatible delivery.
The CRISPR-Cas gene-editing system has long been the focus of research as a promising tool in genome editing. However, the ...
Scientists have taken an important step toward a gene therapy that could one day turn off the extra genetic material that ...
Now, following up on that success, a large Chinese collaboration has followed up with a description of an improved gene ...
Cancer cells excel at evading detection, but subtle chemical differences set them apart from healthy cells. Now, a team of ...
For the millions of people living with genetic diseases like muscular dystrophy and inherited liver disorders, one of the ...
The last time The Lancet Microbe featured an Editorial on CRISPR was in November 2020, to mark that year’s Nobel Prize in Chemistry, jointly awarded to Emmanuelle Charpentier and Jennifer A Doudna for ...