Radioimmunotherapy and nuclear imaging (immuno-PET/SPECT) of cancer with radiometal-labeled antibody fragments or peptides is hampered by low tumor-to-kidney ratios because of high renal radiometal ...

Improving imaging-based response after neoadjuvant chemotherapy (NAC) in breast cancer assessment could obviate histologic confirmation of pathologic complete response (pCR) and facilitate ...

WHY IS FAP-TARGETED THERAPY ATTRACTIVE? FAP-positive CAFs are found in more than 90% of epithelial cancers, therefore representing a potential pan-cancer target (6). Targeting FAP to deplete stromal ...

Journal of Nuclear Medicine September 2026, jnumed.126.272814; DOI: https://doi.org/10.2967/jnumed.126.272814 ...

Inflammatory bowel diseases (IBDs) in humans are characterized in part by aberrant CD4-positive (CD4+) T-cell responses. Currently, identification of foci of inflammation within the gut requires ...

The subjects of this study were those who underwent conventional wbPET imaging for clinical examination, for free medical treatment, or as part of the Japan Agency for Medical Research and Development ...

PET/CT imaging of cancer with combined PET and CT scanners has become a standard component of diagnosis and staging in oncology (1,2). The glucose analog 18 F-FDG has been shown to concentrate in ...

SPECT is used to quantitatively and visually assess the distribution of radioactive biologic markers (tracers) in vivo in order to, for example, study animal models of disease and test new ...

Details of MPI and CTAC image acquisition and interpretation are available in the supplemental materials (16). Additional details on the training population are in Supplemental Table 1. Two separate ...

Design and Development of NeuroSphere PET: A Next-Generation 7-T MR-Compatible Dedicated Brain PET Scanner ...

Journal of Nuclear Medicine April 2025, jnumed.124.268980; DOI: https://doi.org/10.2967/jnumed.124.268980 ...

Journal of Nuclear Medicine June 2026, jnumed.126.272338; DOI: https://doi.org/10.2967/jnumed.126.272338 ...