Cleto Escobedo, Jimmy Kimmel's bandleader and childhood best friend, has died. Look back at this career.

Late-night talk show host Jimmy Kimmel is mourning the death of one of his oldest friends — his show's bandleader, Cleto Escobedo III. Kimmel announced Escobedo's death Tuesday on Instagram, saying “that we are heartbroken is an understatement.

On Tuesday’s episode of 'Jimmy Kimmel Live!,' host Jimmy Kimmel announced he would take the rest of the week off following the death of his best friend and the show’s bandleader, Cleto Escobedo III.

Jimmy Kimmel fought through tears on his talk show while honoring his late bandleader and best friend, Cleto Escobedo III, after the musician's death: 'Cherish your friends — we're not here forever.'

Cleto Escobedo III, the bandleader on 'Jimmy Kimmel Live!,' has died at 59, according to the late-night host. Kimmel dedicated his monologue on Tuesday to his close friend.

Jimmy Kimmel paid an emotional tribute to his friend and band leader Cleto Escobedo in his monologue on Tuesday, Nov. 11.

Cleto Escobedo III, the saxophone-playing bandleader for "Jimmy Kimmel Live!," died Tuesday at age 59. Kimmel paid tribute to his friend on "Live."