For decades, the scientific theory of depression focused on chemicals — serotonin, norepinephrine and dopamine. Nearly every ...

Li’s study, “TIAM1-mediated synaptic plasticity underlies comorbid depression-like and ketamine antidepressant-like actions in chronic pain," was recently published in The Journal of Clinical ...

In this study, researchers used positron emission tomography and a special tracer to study the relationship between the distribution of an important neuronal receptor (AMPA) and the occurrence and ...

How do we think, feel, remember, or move? These processes involve synaptic transmission, in which chemical signals are transmitted between nerve cells using molecular containers called vesicles. Now, ...

A new study by Pitt researchers challenges a decades-old assumption in neuroscience by showing that the brain uses distinct transmission sites—not a shared site—to achieve different types of ...