The researchers realized that it may be possible to obviate disadvantages associated with liquid SNEDDS handling, manufacturing and stability should one convert them to solid state. Hence, the concept ...

There has been a resurgence of interest in nanoemulsions for various pharmaceutical applications since low-energy emulsification methods, such as spontaneous or self-nanoemulsification, have been ...

本综述系统梳理了自纳米乳药物递送系统（SNEDDS）在液态与固态形式下的设计策略、辅料选择、稳定性优化及剂型转化工艺，重点探讨了吸附法、喷雾干燥、热熔挤出等固体化技术面临的挑战与 ...

自纳米乳化系统（SNEDDS）通过自发形成纳米乳液提升难溶性药物的生物利用度，应用涵盖口服、注射、肺部等多途径。近年发展出超饱和、固态及靶向SNEDDS，优化载药量、稳定性和靶向性，并 ...