Kadonaga and his team employed emerging genomic techniques and devised novel computational strategies to unlock the DNA sequence code for the human Initiator. They also discovered that this sequence ...

Superimposed on the genetic sequences coding for amino acids is a second genetic code. This second genetic code, which makes use of dual-use codons, or duons, specifies how genes are controlled. The ...

Identifying functional effects of noncoding variants is a major challenge in human genetics. To predict the noncoding-variant effects de novo from sequence, we ...

Henry M. Kronenberg, Barbara E. McDevitt, Joseph A. Majzoub, Jeremy Nathans, Phillip A. Sharp, John T. Potts and Alexander Rich Proceedings of the National Academy of Sciences of the United States of ...

AMSTERDAM--(BUSINESS WIRE)--Annogen, the Amsterdam based biotech company behind the SuRE™ technology for the functional annotation of the non-coding part of the genome, today announced it has begun a ...

RNA vaccines are a new class of vaccines that are composed of an mRNA sequence coding for a pathogen-specific protein (antigen). Once expressed in the body, the target antigen is recognized by the ...