The dementia associated Tau protein — known for its role in microtubule regulation — has now been found to also play important roles in the nerve signaling and mitochondrial function in the brain. A ...

Using a tool to solve a protein's structure, for most researchers in the world of structural biology and computational chemistry, is not unlike using the Rosetta Stone to unlock the secrets of ancient ...

Peptide mapping is an essential step in characterizing, identifying, and monitoring a wide range of properties of target proteins in biotherapeutic studies. Peptide mapping for biotherapeutic proteins ...

Drug development and production rely on stringent quality controls, reproducibility, and verification. Biopharmaceuticals, including protein-based therapies, require extensive characterization, ...

For the neurons in the brain to work smoothly and be able to process information, the central nervous system needs a strictly regulated environment. This is maintained by the blood-brain barrier, ...

Ahmet Coskun's lab has developed iseqPLA to map protein interactions. An artistic rendering of sub-cellular activity: The cell membrane is seen at the top, nucleus on the bottom/right. Protein pairs ...

BUFFALO, N.Y. – A groundbreaking technique for in-depth mapping of protein localizations in whole tissue developed by researchers in the University at Buffalo School of Pharmacy and Pharmaceutical ...

Mitochondria are responsible for the energy supply of the organism and fulfill functions in metabolic and signaling processes. Researchers at the University Hospital Bonn (UKB) and the University of ...

Researchers have shown how the tau protein, known for its role in dementias, behaves where communication in the brain takes place. For the first time, University of Queensland (UQ) researchers have ...

When Laurent Cocea lost his job in 2002, he immediately set to work creating his own company to solve a problem he had while still employed at Amgen in Toronto. "We had a team of students who spent ...