As our body ages, cells have to divide to replenish those that become worn out or damaged. Most cells also carry the genome in their nucleus, which has to be replicated each time cell division takes ...
A new study suggests the immune system relies on repeated rounds of mutation and competition rather than perfect selection to ...
Weill Cornell Researchers Identify Lymphoma Mutation That Disrupts Critical B-Cell Selection Process
Researchers of the Melnick Lab, led by Prof. Ari Melnick, medicine, recently published a study identifying a key mutation that disrupts the B-cell natural selection process during immune response, ...
New research published in Nature Communications into hidden mutations in mitochondrial DNA has uncovered how high mutational levels coincide with later life and link to aging markers. Mitochondria are ...
Genetic disorders can occur due to mutations in one gene (monogenic), multiple genes (multifactorial inheritance), and mutation in one or more chromosomes. Point mutations are where one nucleotide in ...
Mutation-induced drug resistance is a significant challenge to the clinical treatment of many diseases, as structural changes in proteins can diminish drug efficacy. Understanding how mutations affect ...
Using next generation gene sequencing techniques, cancer researchers at UT Southwestern Medical Center have identified more than 3,000 new mutations involved in certain kidney cancers, findings that ...
A new study tracking thousands of B cells across more than 100 germinal centers in mice reveals how the system consistently ...
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