Enveric Biosciences (ENVB) announced new mechanistic data demonstrating that its lead candidate, EB-003, activates both Gq- ...

Enveric Biosciences ENVB on Thursday shared new mechanistic data demonstrating that its lead candidate, EB-003, activates both Gq- and β-arrestin–mediated signaling downstream of the 5-HT₂A receptor.

G protein-coupled receptors (GPCRs) are expressed on the surface of cells and regulate a range of important functions. Because they are involved in so many sensory and physiological processes, ...

Natural killer (NK) cells are pivotal in the innate immune response against cancer and viral infections, with their presence in tumors correlating to better patient outcomes in various cancers.

New research led by the University of Minnesota Medical School demonstrates that molecules acting as "molecular bumpers" and "molecular glues" can rewire G protein-coupled receptor (GPCR) signaling, ...

Researchers at the University of North Carolina (UNC) at Chapel Hill School of Medicine have revealed the detailed structure of the bitter taste receptor, a protein called TAS2R14, and have shown ...

Scientists from the University of Groningen in the Netherlands have identified receptors and proteins that play a role in cells’ internal buildup of nanoparticles. Many of these receptors and proteins ...

“Tasting Upside-Down - An Unusual Sensing Mechanism was Found in Human Bitter Sensing” A new study revealed that some bitter molecules target their sensor through binding simultaneously at two ...

Successful infection often depends on a pathogen’s ability to evade host immune cell detection through stealthy mechanisms. After a person inhales Mycobacterium tuberculosis (MTB) into their lungs, ...