DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these ...

Researchers have identified HELQ as a key regulator of DNA replication stress responses, explaining why cells lacking the ...

Structural biologists at the University of Wisconsin-Madison today published cryo-electron microscopy structures of the complete bacterial DNA replication restart complex — a molecular machine that le ...

DNA replication is usually a very precise, templated process, but some enzymes are capable of "doodling," which might lead to a new future in medical research.

Inhibiting RNase H2 increases DNA damage and activates immune responses in triple-negative breast cancer, suggesting a ...