Homologous recombination is central to the repair of DNA double-strand breaks and the rescue of stalled replication forks. A pivotal intermediate in this process is the Holliday junction, a four-armed ...
A University of Iowa-led study has revealed the unexpected structure adopted by the DNA repair protein RAD52 as it binds and protects replicating DNA in dividing cells. This new structural and ...
A powerful new discovery reveals that Nup98 a protein once thought to only ferry molecules through the nucleus plays a vital role in safeguarding the most vulnerable areas of DNA. By forming ...
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