Immunization with single-round infectious particles enhances potency of a DNA vaccine against West Nile virus. For dengue, the most advanced candidates are a tetravalent live attenuated vaccine and a ...

The life cycles of many flaviviruses involve viral transfer between vertebrate hosts and mosquito vectors. Viral acquisition by vectors from an infected mammalian host is an essential step in the ...

In a recent article published in the journal Viruses, researchers study the challenges impeding the development of vaccines against flaviviruses, which are single-stranded ribonucleic acid (ssRNA) ...

Remember the 2016 Olympics in Brazil? It was the year Brazil defeated Germany in the final game of the men's football (aka soccer) tournament, but it was also the year when Zika virus made its entry ...

WEST LAFAYETTE, Ind. – Opening doors to the possibility of developing new vaccines and antiviral agents to fight a host of insect-borne diseases, scientists have, for the first time, determined the ...

A new technology to produce safer ‘hybrid’ viruses at high volumes for use in vaccines and diagnostics for mosquito-borne diseases has been developed at The University of Queensland. Researchers from ...

Viruses of the family Flaviviridae, including Japanese encephalitis virus (JEV), Dengue virus (DENV), Zika virus (ZIKV), West Nile virus (WNV), and Tick-borne encephalitis virus, are significant ...

Flaviviruses including West Nile, Zika and dengue can result in significant morbidity and mortality. However, new research suggests that a viral protein may prove vital in the discovery of therapeutic ...

Researchers have identified IPO7 as a carrier of flavivirus core protein into host cell nucleus, paving the way for a new therapeutic approach to a range of diseases. Identifying the molecular ...

The flaviviruses are mosquito-borne viruses that are associated with significant worldwide morbidity and mortality. The dengue viruses (DENV) are members of this group associated with dengue fever, ...

Until now, we have been unaware of any reports of flavivirus encephalitis in New Zealand, but we do acknowledge the possibility. 2 At least one local species of mosquito, Culex quinquefasciatus, is a ...

Researchers have gotten the closest look ever at Zika virus and may have discovered some chinks in its armor. Using cryo-electron microscopy, structural biologist Madhumati Sevvana and colleagues ...