A double-strand break (DSB) is a type of DNA damage where both strands of the DNA helix are cut or broken at the same location, causing a complete discontinuity in the DNA molecule. Unrepaired or ...
Cars patched up after a wreck may look fixed—but never run quite as before. The same may hold true for chromatin, according to a study published in Science on November 6. In response to double-strand ...
An illustration of light purple Cas9 enzyme being guided to light blue DNA against dark blue background. The enzyme Cas9 (top) can cause double-strand breaks in DNA (bottom). Credit: Shutterstock ...
New study shows that in women with BRCA1 or BRCA2 mutations, their breast cells already carry a clear pattern of DNA “damage ...
Like base editing, prime editing offers a safer way to genome editing by relying on a nickase enzyme that “nicks” one DNA strand at a time, rather than cutting both simultaneously. Then, with the ...
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