Almost every cell in our body contains around two meters (6.6 feet) of DNA, packed into a tiny nucleus. Yet for the cell to ...

When DNA is damaged, cellular processes respond and repair the DNA. Inhibiting DNA damage repair can be therapeutically ...

DNA can mimic protein functions by folding into elaborate, three-dimensional structures, according to a new study. DNA can mimic protein functions by folding into elaborate, three-dimensional ...

DNA polymerase ζ (Polζ) has emerged as a key reverse transcriptase in RNA-templated double-strand break repair (RT-DSBR), beyond its canonical role in translesion DNA synthesis (TLS). We present here ...

In our bodies, there are trillions of cells. From white blood cells to skin cells, each type has its own specific function which helps us perform tasks and survive. But what makes up these cells and ...

An animal chromatin-diminution review examines measured genome and nuclear changes in copepods while treating the functions ...

Escherichia colitopoisomerase III (EcTopo3) is a type IA topoisomerase that binds single-stranded DNA (ssDNA) during DNA cleavage and strand passage. Here, we report ...

Human genomic DNA is wrapped around core histone proteins to form nucleosomes, the fundamental units of chromatin. During ...

Supercoiling and looping can transmit mechanical stress along the DNA backbone that can promote the separation of the strands of the double helix at specific distant sites, exposing the DNA bases, ...

Neurons are the anatomical and functional unit of the nervous system, regulating both vital functions and higher functions. Among the very few cells in the body that do not regenerate, these cells ...

For decades, biology textbooks taught that DNA’s story could be told with a single image: two elegant strands twisting in a double helix. That picture is still right, but it is no longer enough.

Eight Myotis genomes connect unusual immune adaptations with DNA repair, cell death and dramatic differences in lifespan.