A new cancer drug, still in the experimental phase, showed near-complete tumour shrinkage in the brain.

Diffuse intrinsic pontine glioma (DIPG) is one of the most devastating pediatric brain tumors. It sits in the brainstem where it cannot be surgically removed, responds poorly to chemotherapy, and ...

Cellares and City of Hope announced a collaboration Jan. 8 to evaluate automated manufacturing for an investigational CAR T cell therapy. The effort will target glioblastoma multiforme, a fast-growing ...

Mary Bird Perkins Cancer Center in Baton Rouge, Louisiana is offering a CAR-T cell-based immunotherapy, which genetically ...

Scientists at the Icahn School of Medicine at Mount Sinai have developed an experimental immunotherapy that takes an unconventional approach to metastatic cancer. Rather than targeting cancer cells ...

UCLA scientists have developed a next-generation CAR-T cell therapy that can overcome the immunosuppressive tumor microenvironment, a protective shield that tumors use to weaken immune cells, block ...

A woman who had been sick for many years with three autoimmune conditions has experienced a remarkable recovery after being ...

A new study shows that chimeric antigen receptor T-cell (CAR-T cell) therapy, previously effective only against blood cancers ...

Chimeric antigen receptor T-cell therapy—CAR T for short—has been a major advance in treating blood cancers like leukemia and ...

A new CAR T-cell therapy attacks supportive cells in the tumor microenvironment that bear the surface protein, uPAR.

Among the most promising tools of cancer therapy, engineered immune cells known as chimeric antigen-receptor (CAR) T cells have already transformed the treatment of blood cancers. Yet, despite their ...