Twelve women showed up on Tuesday at BRCA Chat Montreal — a group that Karen Malkin Lazarovitz helped launched to offer support and information to women who have a BRCA1 or BRCA2 gene mutation. Women ...

After a breast-cancer diagnosis and a separate scare, my mom tested for the BRCA2 gene mutation. Knowing it could be hereditary, I decided to get tested at 23 to see if I also carried the mutation. My ...

A new database and mobile app called BRCA Exchange is making it easier for experts to share information about cancer-related gene mutations. Summary Clinical genetics experts from MSK and other ...

Germline BRCA mutations have an adverse impact on both progression-free and overall survival in patients with hormone receptor-positive/HER2-negative metastatic ...

Deescalated nab-paclitaxel plus carboplatin showed higher efficacy than nab-paclitaxel plus gemcitabine in early-stage TNBC patients. BRCA1/2 mutation carriers exhibited a more pronounced pathologic ...

Lynparza significantly improves iDFS, DDFS, and OS in BRCA1/2 mutation-positive, HER2-negative high-risk breast cancer patients. The trial's six-year analysis shows consistent benefits across all ...

The authors acknowledged that longer follow-up (up to 20 years) may be required to detect a potential survival benefit, ...

Damaging variants in genes involved in a rapid immune response (innate immunity) are significantly linked to earlier breast ...

Preliminary genomic analysis has linked defects in natural killer cell pathways to earlier breast cancer diagnosis in women ...