The role of adenosine in neurodegeneration and neuroregeneration has led to growing attention on adenosine receptors as potential drug targets in a range of brain disorders, including ...

Purines are heterocyclic aromatic molecules that are among the oldest and most influential biochemical compounds in evolutionary history. 1 The purine nucleotide adenosine triphosphate (ATP) is the ...

The regulation and function of sleep is one of the biggest black boxes of today's brain science. A new paper finds that rapid eye movement (REM) sleep is suppressed by adenosine acting on a specific ...

Perhaps the most intriguing implication of recent breakthrough research lies in an unexpected connection: the most rigorous mechanistic dissection of rapid antidepressant action identifies adenosine ...