San Diego Fire-Rescue said the Center Fire at Camino Del Norte and Paseo Montanoso could potentially grow to 100 acres.
A Red Flag Warning remained active for inland and mountain communities through Friday morning, which means it could be another busy day for local fire crews.
Evacuations were ordered on the Cal State Channel Islands campus Thursday morning when a brush fire broke out in Ventura County.
Fire crews are battling a brush fire that broke out Tuesday afternoon off of Friars Road near the Fashion Valley Mall.
Red flag warnings are in effect until Thursday for parts of Los Angeles, Ventura and San Diego due to low humidity and relentless Santa Ana winds.